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R. Darren Wood

R. Darren Wood head shot

Professor

DVM UPEI, DVSc Guelph, Diplomate ACVP

 woodr@uoguelph.ca
 Office: PAHL 3801
 519-824-4120 Ext. 54654

 Lab: PAHL 3820
 519-824-4120 Ext. 54740

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Profile

I am a veterinary clinical pathologist and have been employed with the Ontario Veterinary College at the University of Guelph since 2002. My main roles include teaching veterinary students, training aspiring graduate students, laboratory diagnosis, and research. My main areas of interest include hemostatic diseases in dogs and cats, and microRNA in canine cancer. I am the co-supervisor of the OVC Comparative Hemostasis Laboratory.

Research Interests

Hemostasis/Hematology: canine von Willebrand disease, canine immune mediated hemolytic anemia, characterization of canine protein C, storage lesion in transfusion products, avian hemostasis, microRNA in canine cancer, applied hemostasis method validation.

Current Graduate Students

  • Brooklynn Liversidge - PhD: Seal oil for the treatment of canine osteoarthritis
  • Katherine Morrison - PhD: In vitro effect of chemotherapy on microRNA expression in canine lymphoma
  • Charlotte Apps - DVSc: Correlation of traditional clotting measurements with TEG variables in dogs with IMHA with antemortem or post-mortem evidence of thrombosis

Other Lab Personnel

  • Jessica Duma, MSc - Research Technician
  • Lauren Gatrell, MSc - Support Services Technician

Former Graduate Students

  • James Mori - DVM (OVC), DVSc: MicroRNA profiling of canine mast cell tumours using blood plasma and cytology samples and correlation with tumour grade and clinical outcome, 2025.
  • Dante Meza - DVM (Lima, Peru), DVSc, Diplomate ACVP: Use of microRNA profiles determined from lymph node cytology slides to immunophenotype and prognosticate in canine lymphoma, 2024.
  • Karlee Craig, DVM (OVC), DVSc, Diplomate ACVP. MicroRNA profiling in canine lymphoma, 2018.
  • Astrid Oscos Snowball, DVM (UNAM, Mexico), DVSc. Storage lesions in canine platelet concentrates, 2016.
  • Stephan Tran, BSc, MBS. Effect of chemotherapeutic agents on the microRNA profile of a canine lymphoma cell line, 2016.
  • William Gow, BVM (Perth, Australia), DVSc, Diplomate ACVP.  Plasma micro RNA in canine lymphoma, 2015.
  • Valerie Wong, DVM, MVSc, PhD, Diplomate ACVP. Characterization of canine protein C, 2014.
  • Emmeline Tan, DVM, DVSc, Diplomate ACVP - RBC Antigens in Canine Immune-mediated Hemolytic Anemia, 2010.

Teaching

DVM Program

VETM*3450 Principles of Disease in Veterinary Medicine (Hematology and Cytology)

VETM*4490 Systems Pathology (Hemolymphatic Diseases)

Diagnostic Pathology and Laboratory Medicine Rotation (Hematology, Integrated Case Discussions)

Phase II Leader

Graduate Program

PABI*6030, 6040, 6041 Applied Clinical Pathology I, II, III
PABI*6300, 6320 Clinical Pathology I, II
PABI*6104 Mechanisms of Disease (Hemostasis and Thrombosis)

Professional Experience & Honours

2021 American Society for Veterinary Clinical Pathology President

2019 American Society for Veterinary Clinical Pathology Educator Award

Links

Selected Publications

Search PubMed for additional publications by Dr. Wood.

Ludwig, Latasha; Treleaven, Heather; Moorehead, Roger; Foster, Robert; Wood, Robert Darren; Ali, Ayehsa; Wood, Geoffrey, Classification and prognostication of B-cell and T-cell multicentric lymphoma in dogs using serum microRNAs., Veterinary and Comparative Oncology, Volume 23, Issue 2, 310-319 (April 2025)

Phillips, Erin; Blois, Shauna; Wood, Robert Darren; Abrams-Ogg, Anthony; Monteith, Gabrielle; Cuq, Benoit, Monitoring of rivaroxaban therapy in hypercoagulable dogs, Journal of Veterinary Internal Medicine, Volume 39, Issue 2, e70014 (February 2025)

Ludwig, Latasha; Edson, Michael; Treleaven, Heather; Viloria-Petit, Alicia; Mutsaers, Anthony; Moorehead, Roger; Foster, Robert; Ali, Ayesha; Wood, R. Darren; Wood, Geoffrey, Plasma microRNA signatures predict prognosis in canine osteosarcoma patients, PLOS One, Volume 19, Issue 12, e0311104 (December 2024)

Ludwig, Latasha; Vanderboon, Emma; Treleaven, Heather; Wood, R Darren; Schott, Courtney; Wood, Geoffrey, Patient-matched tumours, plasma, and cell lines reveal tumour microenvironment- and cell culture-specific microRNAs, Biology Open, 13(12):bio060483 (October 2024)

Kornya, Matthew; Abrams-Ogg, Anthony; Blois, Shauna; Wood, R. Darren, Investigation of Platelet Function Analyzer 200 platelet function measurements in healthy cats and cats receiving clopidogrel, Journal of Veterinary Diagnostic Investigation, Volume 35, Issue 6, 664-670 (November 2023)

Kornya, Matthew; Abrams-Ogg, Anthony; Blois, Shauna; Wood, R. Darren; Monteith, Gabrielle, Extended sample storage for platelet function testing in healthy dogs, Veterinary Clinical Pathology, Volume 52, Issue 3, 402-411 (Wiley, June 2023) https://doi.org/10.1111/vcp.13226 

Kornya, Matthew; Abrams-Ogg, Anthony; Blois, Shauna; Wood, R. Darren, Validation of Plateletworks ADP for the ProCyte Dx analyzer, Journal of Veterinary Internal Medicine, Volume 37, Issue 2, 518-527 (March 2023) https://doi.org/10.1111/jvim.16670

Beaufrere, Hugues; Barboza, Trinita; Beaufrere, Hugues; Stark, Ken; Burnett, Alysha; Wood, R. Darren, Effects of Atorvastatin and Rosuvastatin on Blood Lipids in Quaker Parrots (Myiopsitta monachus), Journal of Avian Medicine and Surgery (December 2022) 

Lee, Gary K.C.; Barbosa, Courtney; Andersen, Gitte; Ramirez, Christina J; Kornya, Matthew; et al, Cyclic hematopoiesis in a mixed-breed dog: case report and brief review, Journal of Veterinary Diagnostic Investigation, Volume 34, Issue 6, 1006-1009 (November 2022)   

Shaw, K. E., Bersenas, A. M., Bateman, S. W., Blois, S. L., & Wood, R. D. (2021). Validation of a commercial human ELISA to measure hyaluronic acid concentration in feline plasma. Journal of Veterinary Diagnostic Investigation., doi: 10.1177/10406387211044718. 

Shaw, K. E., Bersenas, A. M., Bateman, S. W., Blois, S. L., Guieu, L. S., R. Darren Wood (2021). Use of serum hyaluronic acid as a biomarker of endothelial glycocalyx degradation in dogs with septic peritonitis. American Journal of Veterinary Research, 82 (7), 566-573. 

Beaufrere, H., Gardhouse, S., Wood, D., & Stark, K. (2020). The plasma lipidome of the Quaker parrot (Myiopsitta monachus). PLoS ONE, 15 (12), e0240449.

Craig, K., Wood, G., Keller, S., Mutsaers, A., & Wood, R. (2019).  MicroRNA profiling in canine multicentric lymphoma.   PLoS ONE. doi.org/10.1371/journal.pone.0226357.

Cuq, B., Blois, S. L., Wood, R., Monteith, G., Abrams-Ogg, A. C., Christian Bedard. (2018). Reproducibility, stability, and biological variability of thrombin generation using calibrated automated thrombography in healthy dogs. Veterinary Clinical Pathology, 47, 218-226, doi: 10.1111/vcp.12602.

Abrams-Ogg, A., Bienzle, D., Ho, K., Blois, S., Wood, R., Patricia Shewen, Sophia Lim, Helen Kocmarek (2018). Prevalence of antinuclear and anti-erythrocyte antibodies in healthy cats. V eterinary Clinical Pathology, 1-5, doi:10.1111/vcp.12570.

Le, K., Beaufrere, H., Chalmers, H., Pinard, C., Wood, D., et al (2017). Retro-orbital and disseminated B-Cell lymphoma in a yellow-collared macaw (Primoliusauricollis). Canadian Veterinary Journal, 58 (7), 707-712.

Saati, S., Abrams-Ogg, A., Blois, S., & Wood, R. (2017). Comparison of Multiplate, Platelet Function Analyzer-200, and Plateletworks in healthy dogs treated with aspirin and clopidogrel. Journal of Veterinary Internal Medicine., doi:10.1111/jvim.14886.

Kubik, A. M., O'Sullivan, T. L., Harding, J. C., Wood, R., & Friendship, R. M. (2017). Hematology and biochemistry reference values of Ontario commercial nursing pigs close to the time of weaning. Canadian Veterinary Journal, 58, 371-376.

Westgarth, S., Blois, S., Wood, R., Verbrugghe, A., & Ma, D. (2017). Effects of omega-3 polyunsaturated fatty acids and aspirin, alone and combined, on canine platelet function. Journal of Small Animal Practice, 1-9, doi: 10.1111/jsap.12776.

Wong, V., Cote, O., Bienzle, D., Hayes, A., & Wood, R. (2016). Endothelial protein C receptor-dependent anti-chemotactic effects of canine protein C. American Journal of Veterinary Research, 78 (2), 186-194.

Calvalido, J., Wood, R., Woods, P., Mutsaers, A., & Wood, G. (2016). Comparison of serum cytokine levels between dogs with multicentric lymphoma and healthy dogs. Veterinary Immunology and Immunopathology, 182, 106-114.

Kim, S. D., Baker, P., Delay, J., & Wood, R. (2016). Thrombomodulin expression in tissues from dogs with systemic inflammatory disease. Veterinary Pathology, 53 (4), 797-802.