Geoffrey A. Wood

Co-Director, Institute for Comparative Cancer Investigation | Co-Leader DOGBONE Research Group | Professor
Ontario Veterinary College, Department of Pathobiology
Research Interests
- Cancer Pathology
- Cross-species comparative cancer genetics
- Biomarkers of cancer in humans and animals
- MicroRNAs in cancer
Current Graduate Students
- Rachael Speare - PhD
- Heather Treleaven – PhD
- Sophia Fernandes - PhD
- Connor Bryant - PhD
- Thompson Worden – MSc
- Brittany Naeckel – MSc
- Arlene Khachadoorian – DVSc
- Norma Forero-Munoz – DVSc
Selected Publications
Ludwig L, Treleaven H, Moorehead R, Foster RA, Ali RA, Wood RD, Wood GA. Differential expression of miRNAs in primary canine appendicular osteosarcoma tissue and pulmonary metastases. Vet Pathol. 2026 Jan;63(1):19-32. doi: 10.1177/03009858251356603.
Lu J, Shao Y, Saw S, Fang H, Song G, Chen Y, Tang Q, Wood G, Wang J, Waterhouse P, Shen J, Khokha R. The histone lysine methyltransferase NSD3 drives osteosarcomagenesis by inactivating ARID3A. Cancer Lett. 2025 Sep 17;633:218045. doi: 10.1016/j.canlet.2025.218045.
Ludwig L, Treleaven H, Khachadoorian A, Degasperi B, Walter I, Stuart D, Foster RA, Wood RD, Ali RA, Wood GA. MicroRNAs in serum and tissue can differentiate splenic hemangiosarcoma from other splenic masses in dogs. Vet Pathol. 2025 Sep;62(5):659-671. doi: 0.1177/03009858251317466.
Ludwig L, Treleaven H, Moorehead R, Foster RA, Wood RD, Ali RA, Wood GA. Classification and Prognostication of B-Cell and T-Cell Multicentric Lymphoma in Dogs Using Serum MicroRNAs. Vet Comp Oncol. 2025 Jun;23(2):310-319. doi: 10.1111/vco.13057.
Ludwig L, Edson M, Treleaven H, Viloria-Petit AM, Mutsaers AJ, Moorehead R, Foster RA, Ali A, Wood RD, Wood GA. Plasma microRNA signatures predict prognosis in canine osteosarcoma patients. PLoS One. 2024 Dec 31;19(12):e0311104. doi: 10.1371/journal.pone.0311104.
Ludwig L, Vanderboon EN, Treleaven H, Wood RD, Schott CR, Wood GA. Patient- matched tumours, plasma, and cell lines reveal tumour microenvironment- and cell culture-specific microRNAs. Biol Open. 2024 Dec 15;13(12):bio060483. doi:10.1242/bio.060483.
Mee MW, Faulkner S, Wood GA, Woods JP, Bienzle D, Coomber BL. Longitudinal Study of Transcriptomic Changes Occurring over Six Weeks of CHOP Treatment in Canine Lymphoma Identifies Prognostic Subtypes. Vet Sci. 2024 Nov 5;11(11):540. doi: 10.3390/vetsci11110540.
Schulman FY, Bertram CA, Meuten DJ, Moore FM, Avallone G, Bartel A, Bolfa P, Camus M, Chambers JK, Dark MJ, Dervisis N, Dobromylskyj MJ, Donovan TA, Foster RA, Krimer PM, Miller A, Milovancev M, Roccabianca P, Selmic LE, Wood GA. Overview of the Veterinary Cancer Guidelines and Protocols group's "Developing, reporting and validating histologic tumor grading systems". Vet Pathol. 2024 Jan;61(1):157-159. doi: 10.1177/03009858231209409.
Wong K, Abascal F, Ludwig L, … Wood GA, Adams DJ, van der Weyden L. Cross-species oncogenomics offers insight into human muscle-invasive bladder cancer. Genome Biol. 2023 Aug 28;24(1):191. doi: 10.1186/s13059-023-03026-4.
Ludwig L, Dobromylskyj M, Wood GA, van der Weyden L. Feline Oncogenomics: What Do We Know about the Genetics of Cancer in Domestic Cats? Vet Sci. 2022 Oct 4;9(10):547. doi: 10.3390/vetsci9100547.
Matsuyama A, Wood GA, Speare R, Schott CR, Mutsaers AJ. Prognostic significance of the urokinase plasminogen activator system in tissue and serum of dogs with appendicular osteosarcoma. PLoS One. 2022 Sep 29;17(9):e0273811. doi: 10.1371/journal.pone.0273811.
Luu AK, Cadieux M, Wong M, Macdonald R, Jones R, Choi D, Oblak M, Brisson B, Sauer S, Chafitz J, Warshawsky D, Wood GA, Viloria-Petit AM. Proteomic Assessment of Extracellular Vesicles from Canine Tissue Explants as a Pipeline to Identify Molecular Targets in Osteosarcoma: PSMD14/Rpn11 as a Proof of Principle. Int J Mol Sci. 2022 Mar 17;23(6):3256. doi: 10.3390/ijms23063256.
Search PubMed for additional publications by Dr. Wood.