Xiaoying Zhang

Ph.D. (Berlin)

Profile

Prof. Dr. ZHANG Xiaoying graduated from Charité- Universitätsmedizin Berlin, einer gemeinsamen Einrichtung der Freien Universität Berlin und der Humboldt-Universität zu Berlin, with postgraduate training and a Ph.D. degree in Pharmacology.

His major research interests are:

• antibody engineering and mechanism understanding, immunoassay and antibiotic residence;
• drug metabolism and drug drug interaction, drug evaluation, food safety.

He has published more than 100 peer reviewed papers in international journals and 8 book editions.

Selected Publications

1. Cui Li, Jinxin He, HaoRen, Enqi Du, Xiaoying Zhang*, Xinping Li. Preparation of a chicken scFv to analyze gentamicin residuein animal derived food products. Analytical Chemistry, 2016, 88(7): 4092-4098.
2. Xiaoying Zhang*, Calvert Rosaleen, Sutton Brian, Doré Katy*. IgY: A key molecule in antibody evolution. Biological reviews. 2017 Mar. 16.
3. Cui Li, Yaoyao Zhang, Sergei A. Eremin, Omar Yakup, Gang Yao, Xiaoying Zhang*. Detection of kanamycin and gentamicin residues in animal-derived food using IgY antibody based ic-ELISA and FPIA. Food Chemistry. 2017, 227: 48-54.
4. Zehui Liu, Yangkun Liu, Yuanyuan Zhang, Yajuan Yang, Jingjing Ren, Xiaoying Zhang*, Enqi Du*. Surface displaying of swine IgG1 Fc enhances baculovirus-vectored vaccine efficacy by facilitating viral complement escape and mammalian cell transduction. Veterinary Research. 2017, 48(1):29.
5. Abdul Rasheed Baloch, Abdul Wahid Baloch, Brian J. Sutton, Xiaoying Zhang*. Antibody Mimetics: Promising complementary agents to animal-sourced antibodies. Critical Reviews in Biotechnology. 2016, 36(2): 268-275.
6. Xuemei Jiang, Jianjun Hu, Thirumalai Diraviyam, Xiaoying Zhang*. Immunoglobulin transporting receptors are potential targets for the immunity enhancement and generation of mammary gland bioreactor. Frontiers in Immunology. 2016, 7: 214.
7. Bin Zhao, Xiaoying Zhang*. Mathematical analysis of multi-antibiotic resistance. International Journal of Cardiology. 2016, 219: 33-37.
8. Zhihui Jiang, Xuemei Jiang, Cui Li, Huiting Xue, Xiaoying Zhang*. Development of an IgY antibody-based immunoassay for the screening of the CYP2E1 inducer/inhibitor from herbal medicines. Frontiers in Pharmacology.2016. 7: 502
9. Wenyan Xie, Zhihui Jiang, Jian Wang, Xiaoying Zhang*, Matthias F. Melzig. Protective effect of hyperoside against acetaminophen (APAP) induced liver injury through enhancement of APAP clearance. Chemico-Biological Interactions. 2016, 246: 11-19.
10. Zhihui Jiang, Jian Wang, Xinping Li, Xiaoying Zhang*. Echiancoside and Cistanchetubulosa (Schenk) R. Wight ameliorates bisphenol A-induced testicular and sperm damage in rats through gonad axis regulated steroidogenic enzymes. Journal of Ethnopharmacology. 2016, 193: 321-328.
11. Wenyan Xie, Meng Wang, Chen Chen, Xiaoying Zhang*, Matthias F Melzig. Hepatoprotective effect of isoquercitrin against acetaminophen-induced liver injury. Life Sciences. 2016, 152: 180-189.
12. Thirumalai Diraviyam, Jinxin He, Chen Chen, Bin Zhao, Antonysamy Michael, Xiaoying Zhang*. Effect of passive immunotherapy against Clostridium difficile infection (CDI): A Systematic Review and Meta-analysis. Immuno Therapy. 2016. 8(5): 649-663.
13. Meng Wang, Zhaoxiang Zhou, Jian Wang, Xiaoying Zhang*.An improved in vitro method for screening toxin and medicine target CYP2E1. Environmental Toxicology and Pharmacology. 2016, 47: 86-91.
14. Zhihui Jiang, Jian Wang,Huiting Xue, Meng Wang, Hai Jiang, Yinku Liang, Alberto C.Dias, Marslin Gregory, Chen Chen, Xiaoying Zhang*. Protective effect of wild Corni Fructus methanolic extract against acute alcoholic liver injury in mice. Redox Report. 2016, 22(6): 338-345
15. Xuemei Jiang, Thirumalai Diraviyam, Xiaoying Zhang*. Affinity purification of egg yolk immunoglobulins (IgY) using a human mycoplasma protein. Journal of Chromatography B. 2016, 1012-1013: 37-41.
16. Jinxin He, Yuan Wang, Xiaoying Zhang*. Preparation of artificial antigen and development of indirect competitive ELISA based on egg yolk-derived immunoglobulin (IgY) for the detection of Acid orange II in food samples. Food Analytical Methods. 2016, 9(2): 378-384.
17. Xuemei Jiang, Xiumei Li, Zhi Yang, Sergei A. Eremin, Xiaoying Zhang*. Evaluation and optimization of three different immunoassays for rapid detection zearalenone in fodders. Food Analytical Methods. 2016, 10(1): 256-262.
18. Xiaoying Zhang*, Thirumalai Diraviyama, Xiumei Li, Gang Yao, Antonysamy Michaeld. Preparation of chicken IgY against recombinant E2 protein of bovine viral diarrhea virus (BVDV) and Development of ELISA and ICA for BVDV detection. Bioscience, Biotechnology, and Biochemistry. 2016, 80(12): 2467-2472.
19. Hongxiu Chen, Fan He, Yuan Sun,Yuzi Luo, HuajiQiu*, Xiaoying Zhang*, Brian J.Sutton. Generation and characterization of chicken-sourced single-chain variable fragments against porcine interferon-gamma. Journal of Immunoassay and Immunochemistry. 2015, 36(1): 27-44.
20. Wenyan Xie, Chen Chen, Zhihui Jiang, Jian Wang, Matthias F. Melzig, Xiaoying Zhang*. Apocynum venetum leaf extract attenuates acetaminophen overdose induced liver injury in mice. The American Journal of Chinese Medicine. 2015, 43(3): 457-476.
21. Meng Wang, Jianguo Sun, Zhihui Jiang, Wenyan Xie, Xiaoying Zhang*. Hepatoprotective effect of kaempferol against alcoholic liver injury in mice. The American Journal of Chinese Medicine. 2015, 43(2): 241-254.
22. Zhihui Jiang, Pervez Ahmed Khoso, Haidong Yao, Ziwei Zhang, Xiaoying Zhang*, Shiwen Xu*. SelW regulates inflammation-related cytokines in response to H₂O₂ in Se-deficient chicken liver. RSC Advances. 2015, 5: 37896-37905.
23. Yuan Wang, Xuemei Jiang, Jinxin He, Thirumalai Diraviyam, Xiaoying Zhang*. Quantitative investigation on correlation between IgG and FcRn during gestation and lactating periods in rat. American Journal of Reproductiv Immunology. 2016, 75(2): 81-85.
24. Jinxin He, Yuan Wang, Xiaoying Zhang*. Preparation of artificial antigen and development of IgY based indirect competitive ELISA for the detection of kanamycin residues. Food Analytical Methods. 2015, 9(3): 744-751.
25. Thirumalai Diraviyam, Bin Zhao, Yuan Wang, Ruediger Schade, Antonysamy Michael and Xiaoying Zhang*. Effect of chicken egg yolk antibodies (IgY) against diarrhea in domesticated animals: A Systematic Review and Meta-analysis. Plos one. 2014, 9(5), e97716.
26. Yuan Wang, Zehua Tian, Thirumalai Diraviyam, Xiaoying Zhang*. Neonatal Fc receptor (FcRn): A novel target for therapeutic antibodies and antibody engineering. Journal of Drug Targeting. 2014, 22(4): 269-278.
27. Zehua Tian; Brian Sutton; Xiaoying Zhang*. Distribution of rat neonatal Fc receptor in the principal organs of neonatal and pubertal rats. Journal of Receptors and Signal Transduction. 2014, 34(2): 137-142.
28. Xiaoshuang Liu, Wenjing Yang, Jinxin He, Jinzi. Zhao, Gutierrez C.E. Justo, Xiaoying Zhang*. Preparation of artificial antigen and egg yolk-derived immunoglobulin (IgY) of florfenicol amine for ELISA assay. Journal of Environmental Science and Health, Part B. 2014, 49(2): 109-115.
29. Jinxin He, Thirumalai Diraviyam, Rüdiger Schade, Xiaoying Zhang*. Chronobiological studies of chicken IgY: Monitoring of infradian, circadian and ultradian rhythms of IgY in blood and yolk of chickens. Veterinary Immunology and Immunopathology. 2014. 160(3-4): 266-272.
30. Wenyan Xie, Xiaoying Zhang*, Tian Wang, S. Du. Pharmacokinetic analysis of cefquinome in healthy chickens. British poultry science. 2013, 54(1): 81-86.