Keith J. Betteridge

BVSc Bristol, MVSc Toronto, PhD Reading, FRCVS

Research Interests

• Understanding the interactions between the early embryo and mother that are essential to the maintenance of pregnancy in the mare.
• Historical aspects of reproductive biology.

Selected Publications

• Betteridge, K.J., Raeside, J.I., Waelchli, R.O., Christie, H.L., Hayes, M.A. (2018) Patterns of conceptus development and of progesterone concentrations in maternal blood preceding spontaneous early pregnancy failure in mares. Reprod Fertil Dev 30:1066-1076 https://doi.org/10.1071/RD17336
• Raeside, J.I., Christie, H.L., Betteridge, K.J. (2015) 5Alpha-reduced steroids are major metabolites in the early embryo proper and its membranes. Biol Reprod 2015 Sep;93(3):77. doi: 10.1095/biolreprod.115.131680. Epub 2015 Jul 29.
• Betteridge, K.J. (2014) Therio-ontology: a personal view of 40 years of farm animal embryo form and function. Theriogenology Jan 1;81(1):85-95. doi: 10.1016/j.theriogenology.2013.09.014. Review.
• Ross, D., Marcot, J.D., Betteridge, K.J., Nascone-Yoder, N., Bailey, C.S., Sears, K.E. (2013) Constraints on mammalian forelimb development: insights from developmental disparity. Evolution Dec;67(12):3645-52. doi: 10.1111/evo.12204. Epub 2013 Sep 12.
• Waelchli, R.O., Betteridge, K.J. (2013) Morphology of twin and triplet equine conceptuses during weeks 3 and 4 of pregnancy. Reprod Fertil Dev 25:762-774. http://dx.doi.org/10.1071/RD12067).
• Raeside, J.I., Christie, H.L., Waelchli, R.O., Betteridge, K.J. (2012) Biosynthesis of estrogen by the early equine embryo proper. Reprod Fert Dev on line early http://dx.doi.org/10.1071/RD11275
• Betteridge, K.J., Waelchli, R.O., Christie, H.L., Raeside, J.I., Quinn, B.A., Hayes, M.A. (2012) Relationship between the timing of prostaglandin-induced luteolysis and effects on the conceptus during early pregnancy in mares. Reprod Fert Dev 24:411-424.
• Betteridge, K.J., Hayes, M.A., Waelchli, R.O., Raeside, J.I. (2012) Towards understanding early embryonic loss in mares: an experimental approach. Clinical Theriogenology 4:349-358.
• Hayes, M.A., Quinn, B.A., Lillie, B.N., Côté, O., Bienzle, D., Waelchli, R.O., Betteridge, K.J. (2012) Changes in various endometrial proteins during cloprostenol-induced failure of early pregnancy in mares. Animal Reproduction 9:XXX (in press).
• Raeside, J.I., Christie, H.L., Waelchli, R.O., Betteridge, K.J. (2009) Estrogen metabolism by the equine embryo proper during the fourth week of pregnancy. Reproduction 138:953-960.
• Hayes, M.A., Quinn, B.A., Keirstead, N.D., Katavolos, P., Waelchli, R.O., Betteridge, K.J. (2008) Proteins associated with the early intrauterine equine conceptus. Reprod Domest Anim 43 Suppl 2:232-237.
• Quinn, B.A., Hayes, M.A., Waelchli, R.O., Kennedy, M.W., Betteridge, K.J. (2007) Changes in major proteins in the embryonic capsule during immobilization (fixation) of the conceptus in the third week of pregnancy in the mare. Reproduction. 134, 161-170.
• Betteridge, K.J. (2007) Equine embryology: an inventory of unanswered questions. Theriogenology 68 Suppl 1:S9-21.
• Arar, S., Chan, K.H., Quinn, B.A., Waelchli, R.O., Hayes, M.A., Betteridge, K.J., Monteiro, M.A. (2007) Desialylation of core type 1 O-glycan in the equine embryonic capsule coincides with immobilization of the conceptus in the uterus. Carbohydr. Res. 342, 1110-1115. Epub 2007 Feb 17.
• Crews, L.J., Waelchli, R.O., Huang, C.X., Canny, M.J., McCully, M.E., Betteridge, K.J. (2007) Electrolyte distribution and yolk sac morphology in frozen hydrated equine conceptuses during the second week of pregnancy. Reprod. Fertil. Dev. 19, 804-814.
• Betteridge, K.J. (2003) A history of farm animal embryo transfer and some associated techniques. Anim Reprod Sci 79:203-244.
• Albihn, A., Waelchli, R.O., Samper, J., Oriol, J.G., Croy, B.A., Betteridge, K.J. (2003) Production of capsular material by equine trophoblast transplanted into immunodeficient mice. Reproduction 125:855-863.
• Betteridge, K.J. (2000) Comparative aspects of equine embryonic development. Anim Reprod Sci 60-61:691-702. Review.
• Waelchli, R.O., Jaworski, T., Ruddock, W.D., Betteridge, K.J. (2000) Estimation of sodium and potassium concentrations in the uterine fluid of mares by microdialysis and ion chromatography. J Reprod Fertil Suppl 56:327-332.