Topics for Zoonoses: Non-Foodborne

Frequency, Distribution and Transmission

Rothenburger JL, Rousseau JD, Weese JS, Jardine CM.
Livestock-associated methicillin-resistant Staphylococcus aureus and Clostridium difficle in wild Norway rats (Rattus norvegicus) from Ontario swine farms.
Can J Vet Res. 2018. Jan;82(1):66-69.

Kylie J, McEwen SA, Boerlin P, Reid-Smith RJ, Weese JS, Turner PV.
Prevalence of antimicrobial resistance in fecal Escherichia coli and Salmonella enterica in Canadian commercial meat, companion, laboratory, and shelter rabbits (Oryctolagus cuniculus) and its association with routine antimicrobial use in commercial meat rabbits.
Prev Vet Med. 2017 Nov; 147: 53-57.

Brankston G, Boughen C, Ng V, Fisman DN, Sargeant JM, Greer AL.
Assessing the impact of environmental exposures and Cryptosporidium infection in cattle on human incidence of cryptosporidiosis in Southwestern Ontario, Canada.
PLoS One. 2018 Apr 26;13(4):e0196573. doi: 10.1371/journal.pone.0196573.

Bondo KJ, Pearl DL, JAnecko N, Boerlin P, Reid-Smith RJ, Parmley J, Jardine CM.
Impact of Season, Demographic and Environmental Factors on Salmonella Occurrence in Raccoons (Procyon lotor) from Swine Farms and Conservation Areas in Southern Ontario.
PLoS One. 2016 Sep 9;11(9):e0161497.

Elnekave E, Van Maanen K, Shilo H, Gelman B, Storm N, Berdenstain S, Berke O, Klement E
Prevalence and risk factors for foot and mouth disease infection in small ruminants in Israel.
Prev Vet Med. 2016 Mar; 125: 82-88 doi: 10.1016/j.prevetmed.2015.12.019.

Elnekave E, Van Maanen K, Shilo H, Gelman B, Storm N, Abed El Khaliq M, Sharir B, Berke O, Klement E
Prevalence and risk factors for foot and mouth disease infection in cattle in Israel.
Prev Vet Med. 2016 Aug; 130:51-59

Currie A, Galanis E, Chacon PA, Murray R, Wilcott L, Kirkby P, Honish L, Franklin K, Farber J, Parker R, Shyng S, Sharma D, Tschetter L, Hoang L, Chui L, Pacagnella A, Wong J, Pritchard J, Kerr A, Taylor M, Mah V, Flint J
Outbreak of Escherichia coli O157:H7 Infections Linked to Aged Raw Milk Gouda Cheese, Canada, 2013.
J Food Prot. 2018 Feb;81:325-331

Ferreira JB, Grgić H, Friendship R, Wideman G, Nagy É, Poljak Z.
Longitudinal study of influenza A virus circulation in a nursery swine barn.
Vet Res. 2017 Oct; 48:63  doi: 10.1186/s13567-017-0466-x.

Bondo KJ, Weese JS, Rouseau J, Jardine CM.
Longitudinal study of Clostridium difficile shedding in raccoons on swine farms and conservation areas in Ontario, Canada.
BMC Vet Res. 2015. Oct; 11 (1): 254

‘Neill TJ, Sargeant JM, Poljak Z.
A systematic review and meta-analysis of phase I inactivated vaccines to reduce shedding of Coxiella burnetii from sheep and goats from routes of public health importance.
Zoonoses Public Health. 2014. Dec; 61(8): 519-533

O’Neill TJ, Sargeant JM, Poljak Z.
The effectiveness of Coxiella burnetii vaccines in occupationally exposed populations: a systematic review and meta-analysis.
Zoonoses Public Health. 2014. Mar; 61(2): 81-96.

Dorjee S, Revie CW, Poljak Z, McNab WB, Sanchez J.
One-Health Simulation Modelling: A Case Study of Influenza Spread between Human and Swine Populations using NAADSM.
Transbound Emerg. Dis. 2014. March.

Linnerth-Petrik NM, Walsh SR, Bogner PN, Morrison C, Wootton SK.
Jaagsiekte sheep retrovirus detected in human lung cancer tissue arrays
BMC Res. Notes. 2014. Mar; 7: 160.

Costa MC, Reid-Smith R, Gow S, Hannon SJ, Booker C, Rousseau J, Benedict KM, Morley PS, Weese JS.
Prevalence and molecular characterization of Clostridium difficile isolated from feedlot beef cattle upon arrival and mid-feeding period.
BMC Vet Res. 2012 Mar. 8:38.

Nesbitt A, Ravel A, Murray R, McCormick R, Savelli C, Finley R, Parmley J, Agunos A, Majowicz SE, Gilmour M
Integrated surveillance and potential sources of Salmonella Enteritidis in human cases in Canada from 2003 to 2009.
Epidemiol Infect. 2011 Dec. Epub.

Costa MC, Staempfli HR, Arroyo LG, Pearl DL, Weese JS.
Epidemiology of Clostridium difficile on a veal farm: prevalence, molecular characterization and tetracycline resistance.
Vet Microbiol. 2011 Sep. 152(3-4):379-384.

Marsh JW, Tulenko MM, Shutt KA, Thompson AD, Weese JS, Songer JG, Limbago BM, Harrison LH.
Multi-locus variable number tandem repeat analysis for investigation of the genetic association of Clostridium difficile isolates from food, food animals and humans.
Anaerobe. 2011 Aug. 17(4):156-160.

Rebelo AR, Parker L, Cai HY.
Use of high-resolution melting curve analysis to identify Mycoplasma species commonly isolated from ruminant, avian, and canine samples.
J Vet Diagn Invest. 2011 Sep. 23(5):932-936.

O’Sullivan T, Friendship R, Blackwell T, Pearl D, McEwen B, Carman S, Slavic D, Dewey C.
Microbiological identification and analysis of swine tonsils collected from carcasses at slaughter.
Can J Vet Res. 2011 Apr. 75(2):106-111.

Atalla H, Gyles C, Mallard B.
Staphylococcus aureus small colony variants (SCVs) and their role in disease.
Anim Health Res Rev. 2011 Jun. 12(1):33-45.

Atalla H, Gyles C, Mallard B.
Persistence of a Staphylococcus aureus small colony variants (S. aureus SCV) within bovine mammary epithelial cells.
Vet Microbiol. 2010 Jul. 143(2-4):319-328.

Weese JS, Wakeford T, Reid-Smith R, Rousseau J, Friendship R.
Longitudinal investigation of Clostridium difficile shedding in piglets.
Anaerobe. 2010 Oct. 16(5):501-504.

Mederos A, Fernandez S, VanLeeuwen J, Peregrine AS, Kelton D, Menzies P, LeBoeuf A, Martin R.
Prevalence and distribution of gastrointestinal nematodes on 32 organic and conventional commercial sheep farms in Ontario and Quebec, Canada (2006-2008).
Vet Parasitol. 2010 Jun. 170(3-4):244-252.

Guthrie AD, Learmount J, VanLeeuwen J, Peregrine AS, Kelton D, Menzies PI, Fernandez S, Martin RC, Mederos A, Taylor MA.
Evaluation of a British computer model to simulate gastrointestinal nematodes in sheep on Canadian farms.
Vet Parasitol. 2010 Nov. 174(1-2):92-105.

Nowell VJ, Poppe C, Parreira VR, Jiang YF, Reid-Smith R, Prescott JF.
Clostridium perfringens in retail chicken.
Anaerobe. 2010 Jun; 16(3):314-315.

Berke, O., Romig, T., von Keyserlingk, M.
Emergence of Echinococcus multilocularis among Red Foxes in northern Germany, 1991 – 2005
Veterinary Parasitology. 2008 Aug; 155(3-4): 319-322.

MacInnes J. I, M. Gottschalk, A. G. Lone, D. S. Metcalf, S. Ojha, T. Rosendal, S. B. Watson, R. M. Friendship
Prevalence of Actinobacillus pleuropneumoniae, A. suis, Haemophilus parasuis, Pasteurella multocida, and Streptococcus suis in representative Ontario swine herds.
Can J Vet Res. 2008 Apr; 72(3):242-248.

Poljak Z, Friendship RM, MacNab B, Carman S, Dewey C.
Investigation of exposure to swine influenza viruses in Ontario finisher herds in 2004 and 2005.
Prev Vet Med. 2008; 83: 24-40.

Poljak Z, C E. Dewey, S. W Martin, J Christensen, S Carman, R M. Friendship
Prevalence of and risk factors for influenza in southern Ontario swine herds in 2001 and 2003.
Can J Vet Res. 2008; 72:7-17.

Keel MK, Brazier JS, Post KW, Weese JS, Songer JG.
Prevalence of PCR ribotypes among Clostridium difficile isolates from pigs, calves and other species.
J Clin Microbiol. 2007 Jun; 45(6):1963-1964.

Mattison K., Shukla A., Cook A., Pollari F., Friendship R., Kelton D., Bidawid S., Farber JM
Human Noroviruses in swine and cattle.
Emerg Infect Dis 2007 Aug; 13(8):1184-1188.

Poljak Z, C E. Dewey, S. W Martin, J Christensen, S Carman, R M. Friendship
Spatial clustering of swine influenza in Ontario on the basis of herd-level disease status with different misclassification errors.
Prev Vet Med. 2007; 81:236-249.

Varela NP, Friendship RM, Dewey CE.
Prevalence of Campylobacter spp isolated from grower-finisher pigs in Ontario.
Can Vet J . 2007; 48:515-518.

Peregrine, A.S., Martin, S.W., Hopwood, D.A., Duffield, T.F., McEwen, B., Hobson, J.C. and Hietala, S.K.
Neospora caninum and Leptospira serovar serostatus in dairy cattle in Ontario.
Canadian Veterinary Journal. 2006; 47:467-470.

Olsen CW, Karasin AI, Carman S, Li Y, Bastien N, Ojkic D, Alves D, Charbonneau G, Henning BM, Low DE, Burton L, Broukhanski G.
Triple Reassortant H3N2 Influenza A Viruses, Canada, 2005.
Emerg Infect Dis. 2006;12:1132-1135.

Zhang, X, McEwen B, Mann E, Martin W.
Detection of clusters of Salmonella in animals in Ontario from 1991 to 2001.
Can Vet J. 2005; 46:517-523

Poljak Z, Dewey C, Friendship R, Martin S, Christensen J, Ojkic D, Wu J, Chow E.
Pig and herd level prevalence of Toxoplasma gondii in Ontario finisher pigs in 2001, 2003, and 2004.
Canadian Journal of Veterinary Research. 2008 Jul; 72(4)::303-310

Basic Research

Huang Y, Robertson GJ, Ojkic D, Whitney H, Lang AS.
Diverse inter-continental and host lineage reassortant avian influenza A viruses in pelagic seabirds
Infect Genet Evol. 2014. Mar; 22: 103-11.

Huang Y, Wille M, Dobbin A, Walzthöni NM, Robertson GJ, Ojkic D, Whitney H, Lang AS.
Genetic structure of avian influenza viruses from ducks of the Atlantic flyway of North America
PLoS One. 2014. Jan 30; 9(1).

Huang Y, Wille M, Benkaroun J, Munro H, Bond AL, Fifield DA, Robertson GJ, Ojkic D, Whitney H, Lang AS.
Perpetuation and reassortment of gull influenza A viruses in Atlantic North America
Virology. 2014. May; 456-457: 353-63.

Wille M, Robertson GJ, Whitney H, Ojkic D, Lang AS.
Reassortment of American and Eurasian genes in an influenza A virus isolated from a great black-backed gull (Larus marinus), a species demonstrated to move between these regions.
Arch Virol.  2011 Jan. 156(1):107-115.

Yule AM, LePage V, Austin JW, Barker IK, Moccia RD.
Repeated low-level exposure of the round goby (Neogobius melanostomas) to Clostridium botulinum type E neurotoxin.
J Wildl Dis. 2006 Jul; 42(3):494-500.

Yule AM, Barker IK, Austin JW, Moccia RD.
Toxicity of Clostridium botulinum type E neurotoxin to Great Lakes fish: implications for avian botulism.
J Wildl Dis. 2006 Jul; 42(3):479-93.

Yule AM, Austin JW, Barker IK, Cadieux B, Moccia RD.
Persistence of Clostridium botulinum neurotoxin type E in tissues from selected freshwater fish species: implications to public health.
J Food Prot. 2006 May; 69(5):1164-7.

Gancz AY, Smith DA, Barker IK, Lindsay R, Hunter B.
Pathology and tissue distribution of West Nile virus in North American owls (family: Strigidae).
Avian Pathol. 2006 Feb; 35(1):17-29.

Drebot MA, Lindsay R, Barker IK, Buck PA, Fearon M, Hunter F, Sockett P, Artsob H.
West Nile virus surveillance and diagnostics: A Canadian perspective.
Can J Infect Dis. 2003 Mar; 14(2):105-14.

Drebot MA, Lindsay R, Barker IK, Artsob H.
Characterization of a human granulocytic ehrlichiosis-like agent from Ixodes scapularis, Ontario, Canada.
Emerg Infect Dis. 2001 May-Jun; 7(3):479-80.
No abstract available.

Letocart M., P. Boerlin, F. Boerlin-Petzold, J. Goudet, G. Baranton, and P. Perolat.
Genetic structure of the genus Leptospira by multilocus enzyme electrophoresis.
Intern. J. System. Bacteriol. 1999; 49:231-238.


Wille M, Huang Y, Robertson GJ, Ryan P, Wilhelm SI, Fifield D, Bond AL, Granter A, Munro H, Buxton R, Jones IL, Fitzsimmons MG, Burke C, Tranquilla LM, Rector M, Takahashi L, Kouwenberg AL, Storey A, Walsh C, Hedd A, Montevecchi WA, Runstadler JA, Ojkic D, Whitney H, Lang AS.
Evaluation of seabirds in Newfoundland and Labrador, Canada, as hosts of influenza A viruses. 
J Wildl Dis. 2014. Jan; 50(1): 98-103.

Olson SH, Parmley J, Soos C, Gilbert M, Latorre-Margalef N, Hall JS, Hansbro PM, Leighton F, Munster V, Joly D.
Sampling strategies and biodiversity of influenza A subtypes in wild boars.
PLoS One. 2014. Mar; 9(3): e9826.

Shearer KE, Harte MJ, Ojkic D, Delay J, Campbell D.
Detection of Leptospira spp. in wildlife reservoir hosts in Ontario through comparison of immunohistochemical and polymerase chain reaction genotyping methods.
Can Vet J. 2014. 55(3): 240-8

Velarde R, Calvin SE, Ojkic D, Barker IK, Nagy E.
Avian influenza virus H13 circulating in ring-billed gulls (Larus delawarensis) in southern Ontario, Canada.
Avian Dis. 2010 Mar. 54:411-419.

Pei Y, Swinton J, Ojkic D, Sharif S.
Genetic characterization of two low pathogenic avian influenza virus H5N1 isolates from Ontario, Canada.
Virus Genes. 2009 Feb;38(1):149-54.

Parmley EJ, Bastien N, Booth TF, Bowes V, Buck PA, Ojkic D, Breault A, et al.
Wild bird influenza survey, Canada, 2005.
Emerg Infect Dis. 2008 Jan; 14(1):84-87.

Gancz AY, Campbell DG, Barker IK, Lindsay R, Hunter B.
Detecting West Nile virus in owls and raptors by an antigen-capture assay.
Emerg Infect Dis. 2004 Dec;10(12):2204-6.

Lindsay R, Barker I, Nayar G, Drebot M, Calvin S, Scammell C, Sachvie C, Fleur TS, Dibernardo A, Andonova M, Artsob H.
Rapid antigen-capture assay to detect West Nile virus in dead corvids.
Emerg Infect Dis. 2003 Nov;9(11):1406-10.

Risk Factors

Meadows SL, Jones-Bitton A, McEwen SA, Jansen J, Patel SN, Filejski C, Menzies P.
Prevalence and risk factors for Coxiella burnetii seropositivity in small ruminant veterinarians and veterinary students in Ontario, Canada.
Can Vet J. 2017 Apr;58(4):397-399.

Meadows S, Jones-Bitton A, McEwen SA, Jansen Patel SN, Filejski C, Menzies.
Coxiella burnetii (Q Fever) Seropositivity and Associated Risk Factors in Sheep and Goat Farm Workers in Ontario, Canada.
Vector Borne Zoonotic Dis. 2016 Oct;16(10):643-9.

Waddell L, Rajic A, Stark K, McEwen SA.
Mycobacterium avium ssp. paratuberculosis detection in animals, food, water and other sources or vehicles of human exposure: A scoping review of the existing evidence.
Prev Vet Med. 2016 Sep 15;132:32-48.

Wilhelm B, Leblanc D, Leger D, Gow S, Deckert A, Pearl DL, Friendship R, Rajić A, Houde A, McEwen S.
Farm-level prevalence and risk factors for detection of hepatitis E virus, porcine enteric calicivirus and rotavirus in Canadian finisher pigs.
Can J Vet Res. 2016 Apr; 80:95-105

Meadows S, Jones-Bitton A, McEwan SA, Jansen J, Patel SN, Filejski C, Menzies P
Coxiella burnetti (Q Fever) serpositivity and associated risk factors in sheep and goat farm workers in Ontario, Canada.
Vector Borne Zoonotic Dis. 2016 Oct; 16: 643-9.

Werden L, Barker IK, Bowman J, Gonzales EK, Leighton PA, Lindsay LR, Jardine CM.
Geography, deer, and host biodiversity shape the pattern of Lyme disease emergence in the Thousand Islands Archipelago of Ontario, Canada.
PLoS One. 2014. Jan; 9(1): e85640.

Ogden NH, Bigras-Poulin M, O’Callaghan CJ, Barker IK, Kurtenbach K, Lindsay LR, Charron DF.
Vector seasonality, host infection dynamics and fitness of pathogens transmitted by the tick Ixodes scapularis.
Parasitology. 2007 Feb;134(Pt 2):209-27. Epub 2006 Oct 11.

Ogden NH, Barker IK, Beauchamp G, Brazeau S, Charron DF, Maarouf A, Morshed MG, O’Callaghan CJ, Thompson RA, Waltner-Toews D, Waltner-Toews M, Lindsay LR.
Investigation of ground level and remote-sensed data for habitat classification and prediction of survival of Ixodes scapularis in habitats of southeastern Canada.
J Med Entomol. 2006 Mar;43(2):403-14.

Ogden NH, Maarouf A, Barker IK, Bigras-Poulin M, Lindsay LR, Morshed MG, O’Callaghan CJ, Ramay F, Waltner-Toews D, Charron DF.
Climate change and the potential for range expansion of the Lyme disease vector Ixodes scapularis in Canada.
Int J Parasitol. 2006 Jan;36(1):63-70. Epub 2005 Oct 5.

Olea-Popelka F., Phelan, J, White P., Mc.Grath, G., Collins J., O’Keeffe, J., Duggan, M., Collins, D., Kelton D., Berke, O. and Martin S.W.
Quantifying badger exposure and the risk of bovine tuberculosis for cattle herds in county Kilkenny, Ireland. A case control study.
Preventive Veterinary Medicine, 75, 34-46, 2006.

Ogden NH, Bigras-Poulin M, O’Callaghan CJ, Barker IK, Lindsay LR, Maarouf A, Smoyer-Tomic KE, Waltner-Toews D, Charron D.
A dynamic population model to investigate effects of climate on geographic range and seasonality of the tick Ixodes scapularis.
Int J Parasitol. 2005 Apr 1;35(4):375-89.

Ogden NH, Lindsay LR, Beauchamp G, Charron D, Maarouf A, O’Callaghan CJ, Waltner-Toews D, Barker IK.
Investigation of relationships between temperature and developmental rates of tick Ixodes scapularis (Acari: Ixodidae) in the laboratory and field.
J Med Entomol. 2004 Jul;41(4):622-33.

Barker IK, Lindsay LR.
Lyme borreliosis in Ontario: determining the risks.
CMAJ. 2000 May 30;162(11):1573-4.
No abstract available.

Lindsay LR, Mathison SW, Barker IK, McEwen SA, Gillespie TJ, Surgeoner GA.
Microclimate and habitat in relation to Ixodes scapularis (Acari: Ixodidae) populations on Long Point, Ontario, Canada.
J Med Entomol. 1999 May;36(3):255-62.

Lindsay LR, Mathison SW, Barker IK, McEwen SA, Surgeoner GA.
Abundance of Ixodes scapularis (Acari: Ixodidae) larvae and nymphs in relation to host density and habitat on Long Point, Ontario.
J Med Entomol. 1999 May;36(3):243-54.

Prevention and Control

van Lieshout LP, Soule G, Sorensen D, Frost KL, He S, Tierney K, Safronetz D, Booth SA, Kobinger GP, Qiu X, Wootton SK.
Intramuscular Adeno-Associated Virus-Mediated Expression of Monoclonal Antibodies Provides 100% Protection Against Ebola Virus Infection in Mice.
J Infect Dis. 2018 Mar 5;217(6):916-925.

Totton SC, Wandeler AI, Ribble CS, Rosatte RC, McEwen SA.
Stray dog population health in Jodhpur, India in the wake of an animal birth control (ABC) program.
Prev Vet Med. 2011 Feb. 90(2-3):215-220.

Totton SC, Wandeler AI, Zinsstag J, Bauch CT, Ribble CS, Rosatte RC, McEwen SA.
Stray dog population demographics in Jodhpur, India following a population control/rabies vaccination program.
Prev Vet Med. 2010 Oct. 97(1):51-57.

Jardine, C., C. Waldner, G. Wobeser, and F. A. Leighton.
Effect of experimental ectoparasite control on Bartonella infections in wild Richardson’s ground squirrels.
Journal of Wildlife Diseases. 2006; 42(4):750-758.

Prevention and Control

Bondo KJ, Pearl DL, Janecko N, Boerlin P, Reid-Smith RJ, Parmley J, Jardine CM.
Epidemiology of Salmonella on the Paws and in the Faeces of Free-Ranging Raccoons (Procyon Lotor) in Southern Ontario, Canada.
Zoonoses Public Health. 2015. September 25

Dutton CJ, Quinnell M, Lindsay R, DeLay J, Barker IK.
Paraparesis in a polar bear (Ursus maritimus) associated with West Nile virus infection.
J Zoo Wildl Med. 2009 Sep;40(3):568-71.

McLelland DJ, Dutton CJ, Barker IK.
Sarcomatoid carcinoma in the lung of an Egyptian fruit bat (Rousettus aegyptiacus).
J Vet Diagn Invest. 2009 Jan;21(1):160-3.

Waltner-Toews D, Jones AQ.
A philosophy and approach to teaching the epidemiology of food-borne, waterborne, and zoonotic diseases.
J Vet Med Educ. 2006 Winter;33(4):598-604.