Immunotherapy for dogs with melanoma

Pet Trust is supporting research that aims to fight cancer in dogs by directing their own immune system to attack cancer cells without the toxic side effects of standard treatments. Dr. Byram Bridle’s project is focused on melanoma, and the proteins called melanoma-associated antigens (MAAs) expressed by tumour cells. Us­ing melanoma samples from the OVC’s tumour bank, vaccines containing MAAs will be used to provoke the body’s cancer-killing immune response. The specimens will be analysed for expression of MAAs and the data will be used to develop vaccines to target the most commonly expressed MAAs in canine melanomas.

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