Research Interests

• Acute colitis in horses
• Colostridium difficile associated diseases
• Exercise-related problems in racehorses
• Acid-Base balance in animals and humans

Links

Stewart Acid-Base Analysis (Equine) v.1-4

Stewart Acid-Base Analysis (Equine) v.2-0

Selected Publications

• Staempfli, H. & Schoster, A. (2018).  Recent Advances in the Diagnosis and Management of Equine Gastrointestinal Diseases.   Veterinary Clinics of North America Equine Practice, 34 (1), 1-180, doi: https://doi.org/10.1016/S0749-0739(18)30004-X. 
   Editors of the vet clinics of north america equine practice issue.One volume 34 2018
• Shaw, S. & Staempfli, H. (2018).  Diagnosis and treatment of undifferentiated and infectious acute diarrhea in the adult horse.   Veterinary Clinics of North America Equine Practice, 34 (1), 39-53,
• Gomez, D., Lofstedt, J., Arroyo, L., Wichtel, M., Staempfli, H. (2017) and McClure, J.T.  Association of unmeasured strong ions with outcome of hospitalized beef and dairy diarrheic calves.   Canadian Veterinary Journal, 58, 1086-1092
• Schoster, A., Staempfli, H., Guardabassi, L., & Weese, S. (2017).  Comparison of the fecal bacterial microbiota of healthy and diarrheic foals at two and four weeks of life.  BMC Veterinary Research, 13, 144-153,
• Schoster, A., Guardabassi, L., Staempfli, H., Abrahams, M., Jalali, m., Scott Weese University of Guelph canada (2016).  The longitudinal effect of a multi-strain probiotic on the intestinal bacterial microbiota of neonatal foals.   Equine Veterinary Journal, 48 (6), 689-696
• Schoster, A., Mosing, M., Jalali, M., Staempfli, H., & Weese, S. (2016).  Effects of transport, fasting and anaesthesia on the faecal microbiota of healthy adult horses.  Equine Veterinary Journal, 48 (5), 595-602
• Costa, M., Stämpfli, H., Allen-Vercow, E., & Weese, J. (2015).  Development of the faecal microbiota in foals.   Equine Veterinary Journal, 48 (6), 681-688
• Costa, M., Stämpfli, H., Allen-Vercow, E., & Weese, J. (2015).  Development of the faecal microbiota in foals.   Equine Veterinary Journal, 48 (6), 681-688
• Schoster, A. & Staemfli, H. (2015).  Epidemiology and antimicrobial resistance of Clostridium difficile with special reference to the horse.   Current Clinical Microbiology Reports, 3 (1), 32-41. March 2016, Volume 3, Issue 1, pp 32-41; invited review article http://link.springer.com/journal/40588
• Schoster, A., Staempfli, H., Abrahams, M., Jalali, M., & Weese, S. (2015).  Effect of a Probiotic on Prevention of Diarrhea and Clostridium difficile and Clostridium perfringens Shedding in Foals.   Journal of Veterinary Internal Medicine, 29 (3), 925-931
• Costa, M., Silva, G., Ramos, R., Staempfli, H., Arroyo, L., Weese SJ (2015).  Characterization and comparison of the bacterial microbiota in different gastrointestinal tract compartments in horses.   The Veterinary Journal, 205 (1), 74-80 
• Costa, M., Staempfli, H., Arroyo, L. G., Allan-Vercoe, E., Gomez, R., Weese JS (2015).  Changes in the equine fecal microbiota associated with the use of systemic antimicrobial drugs.   BMC Veterinary Research, 11 (19), 12
• Staempfli, H., Schoster, A., & Constable, P. D. (2014).  Clinical utility of using the results of serum biochemical analysis for predicting acid-base balance in critically ill horses.   Veterinary Clinical Pathology, 43 (4), 547-556
• Vengust, M., Staempfli, H., Viel, L., & Heigenhauser, G. (2013).  Acetazolamide attenuates transvascular fluid flux in equine lungs during intense exercise.   Journal of Physiology, 591 (18), 4499-513.
• Gomez, D., Lofstedt, J., Stämpfli, H. R., Wichtel, M., Muirhead, T., McClureJT (2013).  Contribution of unmeasured anions to acid-base disorders and its association with altered demeanor in 264 calves with neonatal diarrhea.   Journal of Veterinary Internal Medicine, 27, 1604-1612.
• Schoster, A., Arroyo, L., Staempfli, H., & Weese, S. (2013).  Comparison of microbial populations in the small intestine, large intestine and feces of healthy horses using terminal restriction fragment length polymorphism.   BMC Research Notes, 6 (91),
• Gomez, D., Arroyo, L., Stämpfli, H., Cruz, L., & Oliver, O. (2013).  Physicochemical interpretation of admission acid-base abnormalities in 54 horses with acute severe colitis and diarrhea.   Journal of Veterinary Internal Medicine, 27, 548-553
• Constable, P., Gruenberg, W., Staufenbiel, R., & Staempfli, H. (2013).  Clinicopathologic variables associated with hypokalemia in lactating dairy cows with abomasal displacement or volvulus.   J Am Vet Med Assoc. 2013 Mar 15;242(6):826-35.
• Schoster, A., Arroyo, L., Staempfli, H., Shewen, P., & Weese, J. (2012).  Presence and molecular characterization of Clostridium difficile and Clostridium perfringens in intestinal compartments of healthy horses.   BMC Veterinary Research, 8, 94
• Costa, M., Arroyo, L., Allen Vercoe, E., Stampfli, H., & Weese, S. (2012).  Comparison of the fecal microbiota of healthy horses and horses with colitis by high throughput sequencing of the V3-V5 region of the 16S rRNA gene.   PLoS ONE
• Schoster, A., Stampfli, H., Arroyo, L., Shewen, P., & Weese, J. (2012).  Longitudinal study of Clostridium difficile and antimicrobial susceptibility of Escherichia coli in healthy horses in a community setting.   Veterinary Microbiology, 159 (3-4), 364-370.
• Vengust, M., Kerr, C., Staempfli, H., Pringle, J., Heigenhauser, G. J., Viel L (2011).  Effect of frusemide on transvascular fluid fluxes across the lung in exercising horses.  Equine Veterinary Journal, 43 (4), 451-459.
• Costa, M. C., Staempfli, H., Arroyo, L. G., Pearl, D. L., & Weese, J. S. (2011).  Epidemiology of Clostridium difficile on a veal farm: Prevalence, molecular characterization and tetracycline resistance.   Veterinary Microbiology, 152 (3-4), 379-384.
• Medina-Torres, C. E., Weese, J. S., & Staempfli, H. (2011).  Prevalence of Clostridium difficile in horses.   Veterinary Microbiology, 152 (1-2), 212-215.
• Vengust, M., Staempfli, H., De Moraes, A. N., Teixeiro-Neto, F., viel, L., Heigenhauser G (2010).  Effects of chronic acetazolamide administration on gas exchange and acid-base control in pulmonary circulation in exercising horses.   Equine Veterinary Journal, 38, 40-50.
• Medina-Torres CE, Weese JS, Staempfli HR. Validation of a commercial enzyme immunoassay for detection of Clostridium difficile toxins in feces of horses with acute diarrhea. J Vet Intern Med. 2010 May-Jun;24(3):628-32. Epub 2010 Apr 6.
• Constable PD, Gelfert CC, Füerll M, Staufenbiel R, Stämpfli HR. Application of strong ion difference theory to urine and the relationship between urine pH and net acid excretion in cattle. Am J Vet Res. 2009 Jul;70(7):915-25. PubMed PMID: 19566478.
• Rodriguez-Palacios A, Reid-Smith RJ, Staempfli HR, Daignault D, Janecko N, Avery BP, Martin H, Thomspon AD, McDonald LC, Limbago B, Weese JS. Possible seasonality of Clostridium difficile in retail meat, Canada. Emerg Infect Dis. 2009 May;15(5):802-5.
• Rodriguez-Palacios A, Staempfli HR, Duffield T, Weese JS. Isolation of bovine intestinal Lactobacillus plantarum and Pediococcus acidilactici with inhibitory activity against Escherichia coli O157 and F5. J Appl Microbiol. 2009 Feb;106(2):393-401.
• Rodriguez-Palacios A, Staempfli HR, Duffield T, Weese JS. Clostridium difficile in retail ground meat, Canada. Emerg Infect Dis. 2007 Mar;13(3):485-7.
• Vengust M, Staempfli H, Viel L, Heigenhauser G. Transvascular fluid flux from the pulmonary vasculature at rest and during exercise in horses. J Physiol. 2006 Jan 15;570(Pt 2):397-405. Epub 2005 Nov 3. PMID: 16269434
• Stämpfli H, Taylor M, McNicoll C, Gancz AY, Constable PD. Experimental determination of net protein charge, [A]tot, and Ka of nonvolatile buffers in bird plasma. J Appl Physiol. 2006 Jun;100(6):1831-6. Epub 2006 Jan 19. PMID: 16424070
• Arroyo LG, Stämpfli HR, Weese JS. Potential role of Clostridium difficile as a cause of duodenitis-proximal jejunitis in horses. J Med Microbiol. 2006 May;55(Pt 5):605-8. PMID: 16585649
• Arroyo L., Weese S., Staempfli H. Experimental Clostridium Difficile Enterocolitis in Foals. J Vet Int Med. 2004; 18: 734-738
• Staempfli HR, Constable PD. Experimental determination of net protein charge and Atot and Ka of nonvolatile buffers in human plasma.J Appl Physiol. 2003 Aug;95(2):620-630
• Brojer JT, Stämpfli HR, Graham TE. Effect of extraction time and acid concentration on the separation of proglycogen and macroglycogen in horse muscle samples. Can J Vet Res. 2002 Jul;66(3):201-206.
• Brojer JT, Stämpfli HR, Graham TE. Analysis of proglycogen and macroglycogen content in muscle biopsy specimens obtained from horses. Am J Vet Res. 2002 Apr;63(4):570-575.