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Lynne O'Sullivan

Adjunct Faculty   |   DVM, DVSc., Diplomate ACVIM (Cardiology)


I received my Doctor of Veterinary Medicine degree from the Atlantic Veterinary College, University of Prince Edward Island in 1998. Following graduation, I completed a small animal rotating internship at the Ontario Veterinary College (OVC), University of Guelph. I went on to complete a clinical residency in Cardiology and a Doctor of Veterinary Science graduate degree, investigating dilated cardiomyopathy in the Doberman pinscher, also at OVC from 2000-2003. I received board certification in Cardiology by the American College of Veterinary Internal Medicine (ACVIM) in 2003. I have been a University of Guelph faculty member since late 2003 where I continue to be a part of the clinical Cardiology service in the OVC Health Sciences Centre, teaching veterinary undergraduate and graduate students and contributing to clinical investigations.

Research Interests

Dilated cardiomyopathy in the Doberman pinscher

Echocardiographic assessment of systolic and diastolic function

Canine chronic mitral valve disease

Professional Experience & Honours

Canadian Veterinary Medical Association Teacher of the Year Award, 2015

Pfizer Carl J. Norden Distinguished Teacher Award, 2012


Centre for Cardiovascular Investigations (CCVI): http://www.uoguelph.ca/CardiovascularResearch/index.html

Veterinary Cardiology teaching website (under development): http://www.vetgo.com/cardiology/

Selected Publications

Cheng Y, Hogarth KA, O'Sullivan ML, Regnier M, Pyle WG. 2-Deoxyadenosine triphosphate restores the contractile function of cardiac myofibril from adult dogs with naturally occurring dilated cardiomyopathy. Am J Physiol Heart Circ Physiol. 2016 Jan 1;310(1):H80-91.

Ho KK, Abrams-Ogg AC, Wood RD, O'Sullivan ML, Kirby GM, Blois SL. Assessment of platelet function in healthy sedated cats using three whole blood platelet function tests. J Vet Diagn Invest. 2015 May;27(3):352-60.

Alibhai FJ, Tsimakouridze EV, Chinnappareddy N, Wright DC, Billia F, O'Sullivan ML, Pyle WG, Sole MJ, Martino TA. Short-term disruption of diurnal rhythms after murine myocardial infarction adversely affects long-term myocardial structure and function. Circ Res. 2014 May 23;114(11):1713-22.

Singletary GE, Morris NA, O'Sullivan ML, Gordon SG, Oyama MA. Prospective evaluation of NT-proBNP assay to detect occult dilated cardiomyopathy and predict survival in Doberman Pinschers. J Vet Intern Med. 2012 Nov-Dec;26(6):1330-6.

Summerfield NJ, Boswood A, O'Grady MR, Gordon SG, Dukes-McEwan J, Oyama MA, Smith S, Patteson M, French AT, Culshaw GJ, Braz-Ruivo L, Estrada A, O'Sullivan ML, Loureiro J, Willis R, Watson P. Efficacy of pimobendan in the prevention of congestive heart failure or sudden death in Doberman Pinschers with preclinical dilated cardiomyopathy (the PROTECT Study). J Vet Intern Med. 2012 Nov-Dec;26(6):1337-49.

O'Sullivan ML, O'Grady MR, Pyle WG, Dawson JF. Evaluation of 10 genes encoding cardiac proteins in Doberman Pinschers with dilated cardiomyopathy. Am J Vet Res. 2011 Jul;72(7):932-9.

O'Grady MR, O'Sullivan ML, Minors SL, Horne R. Efficacy of benazepril hydrochloride to delay the progression of occult dilated cardiomyopathy in Doberman Pinschers. J Vet Intern Med. 2009 Sep-Oct;23(5):977-83.

Häggström J, Boswood A, O'Grady M, Jöns O, Smith S, Swift S, Borgarelli M, Gavaghan B, Kresken JG, Patteson M, Ablad B, Bussadori CM, Glaus T, Kovacević A, Rapp M, Santilli RA, Tidholm A, Eriksson A, Belanger MC, Deinert M, Little CJ, Kvart C, French A, Rønn-Landbo M, Wess G, Eggertsdottir AV, O'Sullivan ML, Schneider M, Lombard CW, Dukes-McEwan J, Willis R, Louvet A, DiFruscia R. Effect of pimobendan or benazepril hydrochloride on survival times in dogs with congestive heart failure caused by naturally occurring myxomatous mitral valve disease: the QUEST study. J Vet Intern Med. 2008 Sep-Oct;22(5):1124-35.

O'Grady MR, Minors SL, O'Sullivan ML, Horne R. Effect of pimobendan on case fatality rate in Doberman Pinschers with congestive heart failure caused by dilated cardiomyopathy. J Vet Intern Med. 2008 Jul-Aug;22(4):897-904.

O’Sullivan ML, O’Grady MR, Minors SL. Plasma big endothelin-1, atrial natriuretic peptide, aldosterone, and norepinephrine concentrations in normal Doberman pinschers and Doberman pinschers with dilated cardiomyopathy. J Vet Intern Med 2007; 21(1): 92-99.

O’Sullivan ML, O’Grady MR, Minors SL. Assessment of diastolic function using Doppler echocardiography in normal Doberman pinschers and Doberman pinschers with dilated cardiomyopathy. J Vet Intern Med 2007; 21(1): 81-91.

Minors SL, O’Grady MR, Williams RM, O’Sullivan ML. Primary infundibular stenosis with intact ventricular septum: clinical and echocardiographic features in 13 dogs. J Vet Intern Med 2006; 20(6): 1344-50.

O'Grady MR, O'Sullivan ML. Dilated Cardiomyopathy: An Update. Vet Clin Small Anim 2004; 34:1187-1207.

Search PubMed for additional publications by Dr. O'Sullivan.