Reem Sabry

Assistant Professor

MSc, PhD (Guelph)

sabryr@uoguelph.ca
Office: OVC Rm.3604
519-824-4120 Ext.54955

Profile

Dr. Reem Sabry is a biomedical sciences educator who grew up in Dubai, United Arab Emirates. She began her academic journey at the University of Waterloo, where she earned her Honours Bachelor of Science in Biomedical Sciences. Her research interests in reproductive health led to her pursuit of graduate studies at the University of Guelph, completing both her master’s and doctoral degrees in Biomedical Sciences, with a focus on reproductive toxicology.

Currently, she is leading the Skills-Based Master of Biomedical Sciences (MBS) program at the University of Guelph. With a strong background in teaching and curriculum development, she is dedicated to equipping graduate students with practical, laboratory-based expertise that prepares them for careers in biomedical research and industry.

Research Interests

Epigenetic modifications in oocyte maturation and early embryo development
MicroRNA-mediated control of gene expression in bovine oocytes and granulosa cells

Current Graduate Students

Nicole Andrade - MBS
Alana Coulombe - MBS
Nicholas D'Abadie - MBS
Aislynn Essibrah - MBS
Chella Grattet - MBS
Amanda Harris - MBS
Geeteka Leslie - MBS
Julia Mezenberg - MBS
Andrew Rofaeil - MBS
Alexandra Schmidt - MBS
Samantha Taylor - MBS

Teaching

BIOM*3200 DE - Biomedical Physiology
BIOM*6800 - Gene Expression in Health & Disease
BIOM*6910 - Practicum in Biomedical Sciences
VETM*3470 - Anesthesiology & Pharmacology

Selected Publications

1. Goncalves, T. M., Scandlan, O. L. M., Watson, C. B., Davis, O. S., McIlhargey, F. K., Sabry, R., & Favetta, L. A. (2025). Are BPA effects on Connexins and key downstream microRNAs in bovine COCs correlated to miR-21 expression? Reproductive biology, 25(2), 101026. https://doi.org/10.1016/j.repbio.2025.101026

2. Kuzma-Hunt, A. G., Sabry, R., Truong, V. B., Khokhar, J. Y., & Favetta, L. A. (2024). THC and sperm: Impact on fertilization capability, pre-implantation in vitro development and epigenetic modifications. PloS one, 19(3), e0298697. https://doi.org/10.1371/journal.pone.0298697

3. Floccari, S., Sabry, R., Choux, L., Neal, M. S., Khokhar, J. Y., & Favetta, L. A. (2024). DNA methylation, but not microRNA expression, is affected by in vitro THC exposure in bovine granulosa cells. BMC pharmacology & toxicology, 25(1), 42. https://doi.org/10.1186/s40360-024-00763-5

4. Sabry, R., Gallo, J. F., Rooney, C., Scandlan, O. L. M., Amin, S., Faghih, M., Karnis, M., Neal, M. S., & Favetta, L. A. (2024). Genetic and Epigenetic Profiles of Polycystic Ovarian Syndrome and In Vitro Bisphenol Exposure in a Human Granulosa Cell Model. Biomedicines, 12(1), 237. https://doi.org/10.3390/biomedicines12010237

5. Sabry, R., May, D. R., & Favetta, L. A. (2023). The relationship between miR-21, DNA Methylation, and bisphenol a in Bovine COCs and Granulosa Cells. Front Cell Dev Biol, 11. https://doi.org/10.3389/fcell.2023.1294541

6. Sabry, R., Williams, M., LaMarre, J., & Favetta, L. A. (2023). Granulosa cells undergo BPA-induced apoptosis in a miR-21-independent manner. Experimental cell research, 427(1), 113574. https://doi.org/10.1016/j.yexcr.2023.113574

7. Dufour, J., Sabry, R., Khokhar, J. Y., & Favetta, L. A. (2023). Delta-9 tetrahydrocannabinol (THC) effects on the cortisol stress response in bovine granulosa cells. Toxicology in vitro: 88, 105549. https://doi.org/10.1016/j.tiv.2022.105549

8. Kourmaeva, E., Sabry, R., & Favetta, L. A. (2022). Bisphenols A and F, but not S, induce apoptosis in bovine granulosa cells via the intrinsic mitochondrial pathway. Front. Endocrinol., 13, 1028438. https://doi.org/10.3389/fendo.2022.1028438

9. Sabry, R., Williams, M., Werry, N., LaMarre, J., & Favetta, L. A. (2022). BPA Decreases PDCD4 in Bovine Granulosa Cells Independently of miR-21 Inhibition. Int J Mol Sci, 23(15), 8276. https://doi.org/10.3390/ijms23158276

10. Sabry, R., Nguyen, M., Younes, S., & Favetta, L. A. (2022). BPA and its analogs increase oxidative stress levels in in vitro cultured granulosa cells by altering antioxidant enzymes expression. Mol Cell Endocrinol, 545, 111574. https://doi.org/10.1016/j.mce.2022.111574

11. Nguyen, M., Sabry, R., & Favetta, L. A. (2022). Effects of BPA, BPS, and BPF on Oxidative Stress and Antioxidant Enzyme Expression in Bovine Oocytes and Spermatozoa. Genes, 13(1), 142. https://doi.org/10.3390/genes13010142

12. Sabry R., Saleh AC, Stalker L., LaMarre J. & Favetta LA. (2021) Effects of Bisphenol A and Bisphenol S on microRNA expression during bovine (Bos Taurus) oocyte maturation and early embryo development. Reprod Toxicol 99: 96-108. https://doi.org/10.1016/j.reprotox.2020.12.001

13. Sabry R., Yamate J., Favetta L. & LaMarre J. (2019) MicroRNAs: potential targets and agents of endocrine disruption in female reproduction. J Toxicol Pathol. 32(4): 213-221. https://doi.org/10.1293/tox.2019-0054.