Research Interests

Veterinary Clinical Pharmacology

• Chemical Food Safety: Drug depletion studies and residues in food producing animals.
• Extra label drug use in food producing animals
• Regulation of drug use in veterinary patients
• Pharmacokinetic studies
• Evaluation and veterinary applications of drug delivery systems
• Drug and analyte assay (Mass Spec, HPLC, ELISA, EIA)
• Veterinary clinical trials
• Clinical research including exploratory/discovery studies

Current Graduate Students

Philip
Russell

MSc

Selected Publications

• Milnes, E., Delnatte, P., Woodbury, M., Hering, A., Lee, S., Smith D, Nemeth N, Gu Y, Gehring R & Johnson, R (2019). Pharmacokinetics of imidocarb diproprionate in white-tailed deer (Odoccoileus virginianus) after single intramuscular administration.  Journal of Veterinary Pharmacology and Therapeutics.  DOI:10.1111/jvp.12760.
• Cramer, G., Solano, L., & Johnson, R. (2018). Evaluation of tetracycline levels in milk following extra label administration of topical tetracycline for digital dermatitis in dairy cattle. Journal of Dairy Science; 102(1): 883-895.
• Enouri, S., Guerin, M., Wilson, I., Dowling, P., & Johnson, R. (2018). Tissue residue depletion of fenbendazole after oral administration in turkeys. Canadian Veterinary Journal, 60(3); 282-286.
• Sanchez, A., Valverde, A., Sinclair, M., Mosley, C., Singh, A., Mutsaers AJ, Hanna B, Johnson R, Gu Y, Beaudoin-Kimble M (2017). Antihistaminic and cardiorespiratory effects of diphenhydramine hydrochloride in anesthetized dogs undergoing excision of mast cell tumors.  American Veterinary Medical Association. Journal, 251 (17), 804-813.
• Boison, J., Dowling, P., Matus, J., Kinar, J., & Johnson, R. (2017). The analysis of phenylbutazone and its active metabolite, oxyphenbutazone, in equine tissues (muscle, kidney, liver), urine, and serum by LC-MS/MS. Journal of AOAC International, 100 (4), 1110-1122, doi: https://doi.org/10.5740/jaoacint.16-0127.
• Reimann, J., Dewey, C., Bateman, S. W., Kerr, C., & Johnson, R. (2017). Perioperative analgesic use by Ontario veterinarians, 2012. Canadian Veterinary Journal, 58 (2), 149-156.
• Johnson, R., Kerr, C., Enouri, S., Modi, P., Lascelles, D., delCastillo J (2017). Pharmacokinetics of Liposomal Encapsulated Buprenorphine Suspension Following Subcutaneous Administration to Cats. Journal of Veterinary Pharmacology and Therapeutics, 40 (3), 256-269.
• Beswick, A., Dewey, C., Johnson, R., Dowsett-Cooper, J., & Niel, L. (2016). Survey of Ontario veterinarians' knowledge and attitudes on pain in dogs and cats in 2012. Canadian Veterinary Journal, 57 (12), 1274-1280.
• Keating, S., Kerr, C., McDonell, W., Valverde, A., Johnson, R., Knych H, Edginton A (2016). Effects of acepromazine or dexmedetomidine on fentanyl disposition in dogs during recovery from isoflurane anesthesia. Veterinary Anaesthesia and Analgesia, 43 (1), 35-43.
• Boison, J., Dowling, P., Johnson, R., & Kinar, J. (2016). Analysis of phenylbutazone residues in horse tissues with and without enzyme-hydrolysis by LC-MS/MS. Drug Testing and Analysis, 8, 535-538.
• Sanchez, A., Valverde, A., Sinclair, M., Moseley, C., Singh, A., Mutsaers AJ, Hanna B, Gu Y, Johnson R. (2016). The pharmacokinetics of DPH after the administration of a single intravenous or intramuscular dose in healthy dogs. Journal of Veterinary Pharmacology and Therapeutics, 39 (5), 452-459, doi: 10.1111/jvp.12293.
• O'Sullivan, T., Johnson, R., Poljak, Z., Gu, Y., Delay, J., Friendship R. (2016). An experimental study with a vaccine strain of porcine reproductive and respiratory syndrome virus to determine effects on viremia assessed by reverse transcriptase-polymerase chain reaction in pigs fed rations medicated with tilmicosin or non-medicated. Journal of Swine Health and Production, 24 (2), 81-92.
• Enouri, S., DeKroon, K., Friendship, R., Schrier, N., Dowling, P., Johnson R. (2015). Depletion of bromadiolone in tissues of hogs following oral exposure. Journal of Swine Health and Production, 23 (6), 298-305.