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MSc/PhD position to investigate immune repertoires in inflammatory central nervous system diseases in dogs (pdf file)
A MSc/PhD position is available (pending stipend funding) to investigate immune repertoires in inflammatory central nervous system (CNS) diseases in dogs. Inflammatory central nervous system diseases in dogs are difficult to diagnose due to similar clinical presentations. The project will investigate if different inflammatory CNS diseases in dogs are associated with characteristic adaptive immune responses that could be harnessed diagnostically.
The successful applicant will 1) optimize the methodology to investigate lymphocyte antigen receptor (LAR) gene repertoires in dogs and 2) assess LAR repertoires in cerebrospinal fluid and CNS tissue samples of dogs. Laboratory techniques will include highly multiplexed PCR, capillary gel electrophoresis and high-throughput sequencing. The successful applicant will participate in the computational aspects of data analysis and, if desired, in the clinical or histopathological assessment of cases. A veterinary background is desired but not required.
The position is offered jointly through the labs of Dr. Stefan Keller, Department of Pathobiology (http://pathobiologyresearch.com/keller/) and Dr. Fiona James, Department of Clinical Studies (neurology) starting May or September 2017. The degree will be offered through the Department of Pathobiology, with the option of specialization through the Collaborative Neuroscience Program (http://ovc.uoguelph.ca/biomedical-sciences/collaborative-grad-neuroscience).
Applicants are encouraged to send a statement of interest, their CV, transcripts and the names and contract information of three references to Dr. Stefan Keller at firstname.lastname@example.org or Dr. Fiona James at email@example.com.
Review of applications will begin immediately, and continue until the position is filled. Please note that this position is dependent on stipend funding. Intramural or provincial funding opportunities are available on a competitive basis.
Research-related inquiries, or inquiries about the specific project should be directed to Dr. Keller and/or Dr. James.