Knowledge Synthesis and Translation

CPHAZ members bring together research findings from a larger body of knowledge and analyze using qualitative or quantitative methods in an effort to support human and animal health initiatives. Knowledge synthesis can include systematics reviews, meta-analyses, scoping reviews, risk assessments and practice guidelines. Reviews have always played an critical role in knowledge translation and dissemination of public health research.

General topics in synthesis research

O’Connor A, Sargeant J
Research synthesis in veterinary science: Narrative reviews, systematic reviews and meta-analysis.
Vet. J. 2015. Aug.
Abstract

Lambert K, Coe J, Niel L, Dewey C, Sargeant JM.
A systematic review and meta-analysis of the proportion of dogs surrendered for dog-related and owner-related reasons.
Prev Vet Med. 2015. 118(1): 148-160.
Abstract

Pham MT, Rajić A, Greig JD, Sargeant JM, Papadopoulos A, McEwen SA.
A scoping review of scoping reviews: advancing the approach and enhancing the consistency
Res. Synth. Methods. 2014. Dec; 5(4): 371-85.
Abstract

Mederos A, Waddell L, Sanchez J, Kelton D, Peregrine AS, Menzies P, VanLeeuwen J, Rajic A.
A systematic review-meta-analysis of primary research investigating the effect of selected alternative treatments on gastrointestinal nematodes in sheep under field conditions.
Prev Vet Med. 2012 Apr. 104(1-2):1-14.
Abstract

Kwong, Deardon
Linearized forms of individual-level models for large-scale spatial infectious disease systems
Bulletin of Mathematical Biology. 2012

Macdonald LE, Brett J, Kelton D, Majowicz SE, Snedeker K, Sargeant JM.
A systematic review and meta-analysis of the effects of pasteurization on milk vitamins, and evidence for raw milk consumption and other health-related outcomes.
J Food Prot. 2011 Nov. 74(11):1814-1832.
Abstract

Sargeant JM, Thompson A, Valcour J, Elgie R, Saint-Onge J, Marcynuk P, Snedeker K.
Quality of reporting of clinical trials of dogs and cats and associations with treatment effects.
J Vet Intern Med. 2010 Feb. 24(1):44-50.
Abstract

Deardon R, Brooks SP, Grenfell BT, Keeling MJ, Tildesley MJ, Savill MJ, Shaw DJ, Woolhouse ME
Inference for individual level models of infectious diseases in large populations
Statistica Sinica. 2010. 20(1):239-261.

Thomas MK, Perez E, Majowicz SE, Reid-Smith R, Albil S, Monteverde M, McEwen SA.
Burden of acute gastrointestinal illness in Galvez, Argentina, 2007.
J Health Popul Nutr. 2010 Apr;28(2):149-58.
Abstract

Rumbeiha WK, Agnew D, Maxie G, Hoff B, Page C, Curran P, Powers B.
Analysis of a Survey Database of Pet Food-Induced Poisoning in North America.
J Med Toxicol. 2010 Jun; 6(2):172-184.
Abstract

O’Connor AM, Sargeant JM, Gardner IA, Dickson JS, Torrence ME; Consensus Meeting Participants, Dewey CE, Dohoo IR, Evans RB, Gray JT, Greiner M, Keefe G, Lefebvre SL, Morley PS, Ramirez A, Sischo W, Smith DR, Snedeker K, Sofos J, Ward MP, Wills R.
The REFLECT statement: methods and processes of creating reporting guidelines for randomized controlled trials for livestock and food safety by modifying the CONSORT statement.
Zoonoses Public Health. 2010 Mar 1;57(2):95-104.
Abstract

Kunz R, Nagy E, Coppus SF, Emparanza JI, Hadley J, Kulier R, Weinbrenner S, Arvanitis TN, Burls A, Cabello JB, Decsi T, Horvath AR, Walzak J, Kaczor MP, Zanrei G, Pierer K, Schaffler R, Suter K, Mol BW, Khan KS.
How far did we get? How far to go? A European survey on postgraduate courses in evidence-based medicine.
J Eval Clin Pract. 2009 Dec;15(6):1196-204.
Abstract

Sargeant JM, Elgie R, Valcour J, Saint-Onge J, Thompson A, Marcynuk P, Snedeker K. Methodological quality and completeness of reporting in clinical trials conducted in livestock species. Prev Vet Med. 2009. 92:107-115.
Abstract

Waddell L, Rajic A, Sargeant J, Parker S, Deckert A, McEwen S.
The methodological soundness of literature reviews addressing three potential zoonotic public health issues.
Zoonoses and Public Health. 2009 Nov; 56(9-10):477-489.
Abstract

Dewey C, Haley C, Widowski T, Friendship R, Sunstrum J, Richardson K.
Using data collected for production or economic purposes to research production animal welfare: an epidemiological approach.
J Appl Anim Welf Sci. 2009;12(2):105-13.
Abstract

Duffield TF, Leslie KE, Lissemore KD, Millman ST.
Research and teaching of dairy cattle well being: finding synergy between ethology and epidemiology.
J Appl Anim Welf Sci. 2009;12(2):132-42.
Abstract

Sargeant JM, Torrence ME, Rajic A, O’Connor AM, Williams J.
Methodological quality assessment of review articles evaluating interventions to improve microbial food safety.
Foodborne Pathogens and Disease. 2006; 3(4): 447-456.
Abstract

Sargeant JM, Rajic A, Read S, Ohlsson A.
The process of systematic review and its application in agri-food public health.
Prev. Vet. Med. 2006; 75:141-151.
Abstract

Systematic reviews in food safety related topics

Wisener LV, Sargeant JM, O’Connor AM, Faires MC, Glass-Kaastra SK
The use of direct-fed microbials to reduce shedding of Escherichia coli O157 in beef cattle: a systematic review and meta-analysis.
Zoonoses Public Health. 2015. Mar; 62(2): 75-89.
Abstract

Keithlin J, Sargeant J, Thomas MK, Fazil A.
Systematic review and meta-analysis of the proportion of non-typhoidal Salmonella cases that develop chronic sequelae.
Epidemiol Infect. 2015. May; 143(7): 1333-51
Abstract

Young I, Waddell L, Harding S, Greig J, Mascarenhas M, Sivaramalingam B, Pham MT, Papadopoulos A.
A systematic review and meta-analysis of the effectiveness of food safety education interventions for consumers in developed countries
BMC Public Health. 2015. Aug; 15: 822
Abstract

Sivaramalingam B, Young I, Pham MT, Waddell L, Greig J, Mascarenhas M, Papadopoulos A.
Scoping review of research on the effectiveness of food safety interventions directed at consumers
Foodborne Pathogen Dis. 2015. Jul., 12(7): 561-70.
Abstract

Young I, Kerr A, Waddell L, Pham MT, Greig J, McEwen SA, Rajić A.
A guide for developing plain-language and contextual summaries of systematic reviews in agri-food public health
Foodborne Pathogen Dis. 2014. Dec; 11(12): 930-7.
Abstract

Young I, Waddell L, Sanchez J, Wilhelm B, McEwen SA, Rajić A
The application of knowledge synthesis methods in agri-food public health: recent advancements, challenges and opportunities
Prev. Vet. Med. 2014. Mar; 113(4): 339-55.
Abstract

Sargeant JM, O’Connor AM.
‘One-stop shopping’ for information on conducting systematic reviews and meta-analysis in animal agriculture and veterinary medicine.
Zoonoses Public Health. 2014. June; Suppl 1: 2.
Abstract

Sargeant JM, O’Connor AM.
Introduction to systematic reviews in animal agriculture and veterinary medicine.
Zoonoses Public Health. 2014. June; Suppl 1: 3-9.
Abstract

Sargeant JM, Kelton DF, O’Connor AM.
Study designs and systematic reviews of interventions: building evidence across study designs.
Zoonoses Public Health. 2014. June; Suppl 1: 10–17
Abstract

Sargeant JM, Kelton DF, O’Connor AM.
Randomized controlled trials and challenge trials: design and criterion for validity.
Zoonoses Public Health. 2014. June; Suppl 1: 18-27.
Abstract

O’Connor AM, Anderson KM, Goodell CK, Sargeant JM.
Conducting systematic reviews of intervention questions I: Writing the review protocol, formulating the question and searching the literature.
Zoonoses Public Health. 2014. June; Suppl 1: 28-38.
Abstract

Sarjeant JM, O’Connor AM
Conducting systematic reviews of intervention questions II: Relevance screening, data extraction, assessing risk of bias, presenting the results and interpreting the findings.
Zoonoses Public Health. 2014. June; Suppl 1: 39-51
Abstract

O’Connor A, Sargeant J, Wang C
Conducting Systematic Reviews of Intervention Questions III: Synthesizing Data from Intervention Studies Using Meta-Analysis
Zoonoses Public Health. 2014. June; 61 Suppl 1: 52-63.
Abstract

Wisener LV, Sargeant JM, O’Connor AM, Faires MC, Glass-Kaastra SK.
The evidentiary value of challenge trials for three pre-harvest food safety topics: a systematic assessment.
Zoonoses Public Health. 2014. Nov; 61(7): 449-76.
Abstract

McLinden T, Sargeant JM, Thomas MK, Papadopoulos A, Fazil A
Component costs of foodborne illness: a scoping review
BMC Public Health. 2014. May., 14: 509.
Abstract

Keithlin J, Sargeant J, Thomas MK, Fazil A.
Systematic review and meta-analysis of the proportion of Campylobacter cases that develop chronic sequelae.
BMC Public Health. 2014. Nov; 14: 1203
Abstract

Keithlin J, Sargeant J, Thomas MK, Fazil A.
Chronic sequelae of E. coli O157: systematic review and meta-analysis of the proportion of E. coli O157 cases that develop chronic sequelae.
Foodborne Pathogen Dis. 2014. Feb; 11(2): 79-95
Abstract

O’Connor A, Sargeant J
An introduction to systematic reviews in animal health, animal welfare, and food safety
Anim. Health Res. Rev. 2014. Jun; 15(1): 3-13.
Abstract

O’Connor A, Sargeant J
Finally, the opportunity to publish systematic review protocols, systemic reviews and guidelines in animal health, animal welfare, and food safety.
Anim. Health Res. Rev. 2014. Jun; 15(1): 1-2.
Abstract

McLinden T, Sargeant JM, Thomas MK, Papadopoulos A, Fazil A
Component costs of foodborne illness: a scoping review
BMC Public Health. 2014. May., 14: 509.
Abstract

Majowicz SE, Scallan E, Jones-Bitton A, Sargeant JM, Stapleton J, Angulo FJ, Yeung DH, Kirk MD.
Global indidence of human Shiga toxin-producting Escherichia coli infections and deaths: a systematic review and knowledge synthesis.
Foodborne Pathogen Dis. 2014. Jun., 11(6): 447-55.
Abstract

Tusevljak N, Rajic A, Waddell L, Dutil L, Cernicchiaro N, Greig J, Wilhelm BJ, Wilkins W, Totton S, Uhland FC, Avery B, McEwen SA.
Prevalence of Zoonotic Bacteria in Wild and Farmed Aquatic Species and Seafood: A Scoping Study, Systematic Review, and Meta-analysis of Published Research.
Foodborne Pathog Dis. 2012 May. Epub.
Abstract

Bucher O, Farrar AM, Totton SC, Wilkins W, Waddell LA, Wilhelm BJ, McEwen SA, Fazil A, Rajic A.
A systematic review-meta-analysis of chilling interventions and a meta-regression of various processing interventions for Salmonella contamination of chicken.
Prev Vet Med. 2012 Jan. 103(1):1-15.
Abstract

Bucher O, Fazil A, Rajic A, Farrar A, Wills R, McEwen SA.
Evaluating interventions against Salmonella in broiler chickens: applying synthesis research in support of quantitative exposure assessment.
Epidemiol Infect. 2012 May. 140(5):925-945.
Abstract

Snedeker KG, Canning P, Totton SC, Sargeant JM.
Completeness of reporting in abstracts from clinical trials of pre-harvest interventions against foodborne pathogens.
Prev Vet Med. 2012 Apr. 104(1-2):15-22.
Abstract

Sargeant JM, O’Connor AM, Renter DG, Kelton DF, Snedeker K, Wisener LV, Leonard EK, Guthrie AD, Faires M.
Reporting of methodological features in observational studies of pre-harvest food safety.
Prev Vet Med. 2011 Feb. 98(2-3):88-98.
Abstract

Snedeker KG, Campbell M, Totton SC, Guthrie A, Sargeant JM.
Comparison of outcomes and other variables between conference abstracts and subsequent peer-reviewed papers involving pre-harvest or abattoir-level interventions against foodborne pathogens.
Prev Vet Med. 2010 Nov. 97(2):67-76.
Abstract

Snedeker KG, Totton SC, Sargeant JM.
Analysis of trends in the full publication of papers from conference abstracts involving pre-harvest or abattoir-level interventions against foodborne pathogens.
Prev Vet Med. 2010 Jun 1;95(1-2):1-9.
Abstract

Guerin MT, Sir C, Sargeant JM, Waddell L, O’Connor AM, Wills RW, Bailey RH, Byrd JA.
The change in prevalence of Campylobacter on chicken carcasses during processing: a systematic review.
Poult Sci. 2010 May. 89(5):1070-1084.
Abstract

Sargeant JM, Saint-Onge J, Valcour J, Thompson A, Elgie R, Snedeker K, Marcynuk P.
Quality of reporting in clinical trials of preharvest food safety interventions and associations with treatment effect.
Foodborne Pathog Dis. 2009 Oct;6(8):989-99.
Abstract

O’Connor AM, Deagamage T, Sargeant JM, Rajic A, McKean J.
Feeding management practices and feed characteristics associated with Salmonella prevalence in live and slaughtered market-weight finisher swine: A systematic review and summation of evidence from 1950 to 2005.
Prev Vet Med. 2008; 87:213-228.
Abstract

Denagamage, T, O’Connor AM, Sargeant JM, Rajic A, McKean JD.
Efficacy of vaccination to reduce Salmonella prevalence in live and slaughtered swine: A systematic review of literature from 1979 to 2007.
Foodborne Pathogens and Disease. 2007; 4(4):539 – 549.
Abstract

Sargeant JM, Amezcua MR, Rajic A, Waddell L.
Pre-harvest interventions to reduce the shedding of E. coli O157 in the faeces of weaned domestic ruminants: A systematic review.
Zoonoses and Public Health. 2007; 54: 260-277.
Abstract

Systematic reviews on topics related to zoonotic disease

Pons W, Young I, Truong J, Jones-Bitton A, McEwen S, Pintar K, Papadopoulos A.
A Systematic Review of Waterborne Disease Outbreaks Associated with Small Non-Community Drinking Water Systems in Canada and the United States.
PLoS One, October, 10. 2015
Abstract

O’Neill TJ, Sargeant JM, Poljak Z.
A systematic review and meta-analysis of phase I inactivated vaccines to reduce shedding of Coxiella burnetii from sheep and goats from routes of public health importance.
Zoonoses Public Health. 2014. Dec; 61(8): 519-533
Abstract

O’Neill TJ, Sargeant JM, Poljak Z.
The effectiveness of Coxiella burnetii vaccines in occupationally exposed populations: a systematic review and meta-analysis.
Zoonoses Public Health. 2014. Mar; 61(2): 81-96.
Abstract

Snedeker KG, Campbell M, Sargeant JM.
A systematic review of vaccinations to reduce the shedding of Escherichia coli O157 in the faeces of domestic ruminants.
Zoonoses Public Health. 2012 Mar. 59(2):126-138.
Abstract

Guerin MT, Sir C, Sargeant JM, Waddell L, O’Connor AM, Wills RW, Bailey RH, Byrd JA.
The change in prevalence of Campylobacter on chicken carcasses during processing: a systematic review.
Poult Sci. 2010 May. 89(5):1070-1084.
Abstract

O’Connor AM, Auvermann B, Bickett-Weddle D, Kirkhorn S, Sargeant JM, Ramirez A, Von Essen SG.
The association between proximity to animal feeding operations and community health: a systematic review.
LoS One. 2010 Mar 10;5(3):e9530.
Abstract

Waddell LA, Rajic A, Sargeant J, Harris J, Amezcua R, Downey L, Read S, McEwen SA.
The zoonotic potential of Mycobacterium avium spp. paratuberculosis: A systematic review.
Can J Public Health. 2008; 99:145 – 155.
Abstract

Risk assessments

Wilhelm B, Waddell L, Greig J, Rajić A, Houde A, McEwen SA.
A scoping review of the evidence for public health risks of three emerging potentially zoonotic viruses: hepatitis E virus, norovirus, and rotavirus
Prev. Vet. Med. 2015. April’ 119(1-2): 61-79.
Abstract

Alton GD, Pearl DL, Bateman KG, McNab WB, Berke O.
Suitability of sentinel abattoirs for syndromic surveillance using provincially inspected bovine abattoir condemnation data.
BMC Vet Res. 2015. Feb.
Abstract

O’Connor AM, Auvermann BW, Higgins JP, Kirychuk SP, Sargeant JM, Von Essen SG, Glanville JM, Wood H.
The association between proximity to animal-feeding operations and community health: a protocol for updating a systematic review.
Syst. Rev. 2014. Sept; 3: 99
Abstract

Young B, Dewey CE, Friendship RM.
Management factors associated with farrowing rate in commercial sow herds in Ontario.
Can Vet J. 2010 Feb;51(2):185-9.
Abstract

Glass SK, Pearl DL, McEwen SA, Finley R.
Canadian province-level risk factor analysis of macrolide consumption patterns (2000-2006).
Antimicrob Chemother. 2010 Jan;65(1):148-55.
Abstract

Alton GD, Pearl DL, Bateman KG, McNab WB, Berke O.
Factors associated with whole carcass condemnation rates in provincially-inspected abattoirs in Ontario 2001-2007: implications for food animal syndromic surveillance.
BMC Vet Res. 2010 Aug. 6:42.
Abstract

Cramer G, Lissemore KD, Guard CL, Leslie KE, Kelton DF.
Herd-level risk factors for seven different foot lesions in Ontario Holstein cattle housed in tie stalls or free stalls.
J Dairy Sci. 2009 Apr; 92(4):1404-11.
Abstract

Olea-Popelka FJ, Fitzgerald P, White P, McGrath G, Collins JD, O’Keeffe J, Kelton DF, Berke O, More S, Martin SW.
Targeted badger removal and the subsequent risk of bovine tuberculosis in cattle herds in county Laois, Ireland.
Prev Vet Med. 2009 Mar 1; 88(3):178-84.
Abstract

Lefebvre S. L., R. Reid-Smith, P. Boerlin, J. S. Weese.
Evaluation of the risks of shedding Salmonellae and other potential pathogens by therapy dogs fed raw diets in Ontario and Alberta.
Zoonoses Public Health. 2008; 55:470-80.
Abstract

Boermans HJ, Leung MC.
Mycotoxins and the pet food industry: toxicological evidence and risk assessment.
Int J Food Microbiol. 2007 Oct 20;119(1-2):95-102. Epub 2007 Aug 19. Review.
Abstract

Jones AQ, Dewey CE, Doré K, Majowicz SE, McEwen SA, Waltner-Toews D.
Exposure assessment in investigations of waterborne illness: a quantitative estimate of measurement error.
Epidemiol Perspect Innov. 2006 May 26;3:6.
Abstract

Jordan, D., McEwen, S.A., Lammerding, A.M. McNab, B., and Wilson, J.B.
Pre-slaughter control of Escherichia coli O157 in beef cattle: a simulation study.
Prev. Vet. Med. 1999; 41:55-74.
Abstract